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Gallbladder events rise modestly, especially with rapid loss. Less common signals include skin dysesthesia, which is now on the label, and a small thyroid-cancer association in two population studies with a tiny absolute event rate. Depression and suicidality remain unproven

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[DOI] [PubMed] [Google Scholar] 15.Sztalryd C, Xu G, Dorward H, Tansey JT, Contreras JA, Kimmel AR, et al

Special populations, such as post-bariatric surgery patients and those on metformin, may require tailored dosing regimens to ensure adequate vitamin B12 levels

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